![]() – In conjunction with the Antagonist/Short Protocol, your fertility doctor may advise you to administer an estrogen patch, and possibly a few days of GnRH antagonist, even before day 1 of a cycle. In some women who respond poorly to the short protocol (e.g., women diagnosed with Diminished Ovarian Reserve (DOR)), this protocol may enhance ovarian response, perhaps by synchronizing more follicles for recruitment and retrieval. By adding “internal production” of FSH to the “external FSH” being administered as fertility medications, this protocol often results in enhanced responsiveness of the ovaries and an increased number of oocytes retrieved.Īlternative IVF Protocols Estrogen Priming Protocol:.You’ll continue to take the microdose of Lupron during the stimulation phase up until the Human Chorionic Gonadotropin (hCG) trigger injection.If you have had a poor response to other protocols or are of advanced maternal age, your fertility doctor might recommend a lower dose of Lupron that stimulates, rather than suppresses, the body’s natural production of FSH. The Flare Protocol or Microdose Lupron Co-Flare Protocol: This allows the FSH and LH from the injectables to control your cycle and prevents premature ovulation of the follicles. When given before as part of the “long protocol,” Lupron temporarily stops the pituitary gland in the brain from secreting FSH and LH. ![]() By week three, your doctor will administer an injectable medication called Lupron.You may be instructed to use birth control pills before you start an IVF cycle.This protocol may be used in younger patients or in patients who have poor embryo quality from other protocols. Lupron Down Regulation, or Long Lupron Protocol: Your doctor may use a “Lupron trigger” or “dual trigger” to stimulate the final maturation of the oocytes prior to retrieval and significantly decrease the risk of Ovarian Hyperstimulation Syndrome (OHSS).Starting around the fifth day, the Gonadotropin-Releasing Hormone (GnRH) antagonist is added to prevent premature ovulation. For 10 days, you’ll take follicle-stimulating hormone (FSH) and lutenizing hormone (LH) injections.You may be instructed to use birth control pills prior to starting an IVF cycle.It involves the fewest number of injections and is effective for the majority of patients. This is the most commonly used IVF protocol. Traditional IVF Protocols Antagonist Protocol or Short Protocol: Learn more and talk to your fertility doctor to decide what’s best for you. With each, the goal is to retrieve the optimal number of eggs required to obtain enough healthy embryos to result in at least one pregnancy.Įach type of IVF protocol, whether it’s a traditional protocol or an alternative protocol, has its own process and is best for different types of patients. In an era of personalized medicine, there are several protocols that can be used to stimulate the ovaries of in vitro fertilization (IVF) patients. ![]()
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